LeoF_225 Yep. I'd make this even simpler before digging into anything complicated.
Next time it happens, don't reboot immediately.
1. Open Task Manager.
2. Sort Processes by Memory.
3. Then sort by CPU.
4. Then check Disk.
5. Look at the Performance tab and see whether Memory, Disk, or CPU is actually pinned.
Take a screenshot.
The important part is catching it while it's slow. Checking Task Manager five minutes after reboot usually tells you almost nothing.
I've seen people spend hours disabling Windows services when the actual culprit was Chrome, a sync client, or one badly behaved app that had been sitting open all day.